How Statin Medications Works? What is Statins list? When Statins are bad for us?

 

 

How Statin Medications Works?

Statins are medications used to reduce high levels of cholesterol.

Statins:

Therapeutic Category: AntiHyperlipidaemia, Drug Category: HMG CoA reductase inhibitors.

These are prescription medicines used to bring down high cholesterol level to normal.

Statins works by decreasing LDL (low-density lipoprotein) or bad cholesterol and by increasing HDL (high-density lipoprotein) or good cholesterol. LDL is bad lipoprotein produced inside arteries.

HDL is good  lipoprotein because it helps by bringing cholesterol to liver, which removes it out of the body.

Statins effects the cholesterol synthesis in liver by inhibiting an enzyme called HMG CoA reductase, needed to create cholesterol. Our body makes 75% of our cholesterol, so by affecting the synthesis of cholesterol in liver can make a big difference. Rest of our body’s cholesterol is from what we’re eating.

Bad Cholesterol Diet

Good Cholesterol Diet

Statins also help liver in getting rid of more cholesterol.

Statins by decreasing cholesterol level in body can decrease the chance of a heart attack or stroke.

Cholesterol is utilized by body in making of vitamin D, hormones and the acid used to digest food. But too much levels of cholesterol in blood can hinders in blood flow in vessels.

Higher level of cholesterol in blood leading to narrowing of the arteries by making Plaque formation (obstacles), these plaques are unstable and can break down and flow with bloodstream, which may cause blockage of artries, leading to heart attack.

In America statins are most common class of drugs, which is used by more than 40 million adults.

 

 

What is Statins list?

Types of statin drugs

Atorvastatin.

Fluvastatin.

Lovastatin (Mevacor® or Altoprev™).

Pitavastatin (Livalo® or Zypitamag®).

Pravastatin. (Crestor® or Ezallor Sprinkle®).

Rosuvastatin

Simvastatin (Flolipid® or Zocor®).

Sometimes, statins are manufactured in combination form in one tablet with another medicine, such as:

Simvastatin with ezetimibe or niacin.

Atorvastatin with ezetimibe or amlodipine.

Lovastatin with niacin.

 

When Statins are bad for us?

Common side effects are:

·         Headache

·         Dizziness

·         Feeling sick

·         Tiredness or Weak physically

·         Constipation

·         Diarrhoea

·         Indigestion

·         Pain in muscles

·         Sleep disturbances

·         Low platelet count in blood

What are Side effects of Statins?👇